Pipeline of regenerative cell therapies

Pipeline

Dedicated to developing regenerative cell therapies the right way,
supported by clinical evidence and approved by the FDA.

Pipeline Overview

Indication
icon of spreedsheet
Pre-Clinical
icon of patient
Feasibility Study
icon of patient group
Pivotal Study
graphic outline of the skeletal system

Partial-thickness
Rotator Cuff Tear

(Shoulder Pain)

Facet Joint Syndrome

(Lower back pain)

Wrist Osteoarthritis

(Wrist pain)

Select Category

Rotator Cuff indication graphic Partial-Thickness Rotator Cuff Tear
Facet Joint Syndrome graphic Facet Joint Syndrome
wrist osteoarthritis indication graphic Wrist Osteoarthritis
image of InGeneron's rotator cuff tendinopathy pipeline

Clinical Trial Status

  • Rotator cuff feasibility study is completed
  • Feasibility study data analyzed and published
  • Pivotal study is actively enrolling patients
  • FDA approval application will follow completion of pivotal trial
internal graphic of a rotator cuff tear

Partial-Thickness Rotator Cuff Tear

Every year, more than one million patients in developed economies experience a tear in their supraspinatus tendon, located within their rotator cuff. This is by far the most common orthopedic shoulder injury, and it results in shoulder pain and sometimes an occupational disability. This condition occurs frequently among elderly people, as well as middle-aged patients who are actively involved in athletics that require a frequent overhead movement of their arms and shoulders.

Diagram of alternative methods from InGeneron's regenerative cell therapeutic approach

Current Treatment Options

A significant number of partial-thickness rotator cuff tear patients undergo surgery or nonsurgical treatment, to relieve the pain that rotator cuff tendinopathy causes and increase the functioning of their rotator cuff and achieve tendon-to-bone healing. Surgical treatment allows repair utilizing an open or arthroscopic procedure. A recent meta-analysis indicates that these operative techniques may not offer future potential to heal tissue better or improve clinical results.

extracting unwanted debris from the vile

InGeneron’s Solution

Doctors who treat partial-thickness rotator cuff tear patients in our trial harvest a small sample of adipose tissue under local anesthesia from the patient’s abdominal area; isolate the regenerative cells from the sample using our cell processing unit and an enzyme; and then wash, filter, and inject the cells into that same patient’s shoulder.

The procedure is performed in the clinic on an outpatient basis and generally takes only two hours, from start to finish.

Learn More About This Trial
image of InGeneron's facet joint syndrome pipeline

Clinical Trial Status

  • Pre-clinical research has been published
  • Facet joint feasibility study is currently enrolling patients
  • Study results will be published upon trial completion
graphic indication for area of back pain

Facet Joint Syndrome

At least two and a half million people endure chronic back pain, and facet joint syndrome is one of the leading cause of this condition. Facet joint syndrome is associated with the inflammation of a person’s facet joint, which leads to degeneration and cartilage loss.

Pain Medication. Corticosteroid injection. Nerve ablation treatment.

Current Treatment Options

Many current treatment options to address facet joint syndrome—such as oral pain medication, steroid injection, and nerve ablation—focus on its symptoms rather than its root cause, and therefore provide only short-term relief rather than healing. Spinal fusion,
a procedure to repair the problem, involves major surgery.

extracting unwanted debris from the vile

InGeneron’s Solution

Doctors who treat Facet Joint Syndrome patients in our trial harvest a small sample of adipose tissue under local anesthesia from the patient’s abdominal area; isolate the regenerative cells from the sample using our cell processing unit and an enzyme; and then wash, filter, and inject the cells into that same patient’s facet joint.

The procedure is performed in the clinic on an outpatient basis and generally takes only two hours, from start to finish.

Learn More About This Trial
image of InGeneron's wrist osteoarthritis pipeline

Clinical Trial Status

  • Pre-clinical research has been published
  • Wrist osteoarthritis feasibility study is currently enrolling patients
  • Study results will be published upon trial completion
graphic diagram for wrist osteoarthritis pain indication

Wrist Osteoarthritis

Each year, at least 100,000 people who develop wrist osteoarthritis need an alternative to surgery to treat their ailment. Wrist osteoarthritis can result in bone spurs and bone cysts in the wrist, as well as a degeneration of cartilage. These conditions can cause inflammation and pain and can lead to a reduction in grip strength and limited range of motion.

Stock image of doctor checking for wrist pain

Current Treatment Options

There are nonsurgical and surgical interventions to address wrist osteoarthritis, but these options sometimes do not offer long-term pain relief or a significant improvement in grip strength.

extracting unwanted debris from the vile

InGeneron’s Solution

Doctors who Wrist Osteoarthritis patients in our trial harvest a small sample of adipose tissue under local anesthesia from the patient’s abdominal area; isolate the regenerative cells from the sample using our cell processing unit and an enzyme; and then wash, filter, and inject the cells into that same patient’s wrist.

The procedure is performed in the clinic on an outpatient basis and generally takes only two hours, from start to finish.

Learn More About This Trial