Adipose-Derived Regenerative Cells (ADRC)
Adipose-derived regenerative cells (ADRC) are cells derived from adipose tissue with stem cell and wound repair capability that include several cell types, such as e.g. adult stem cells, vascular endothelial cells, and vascular smooth muscle cells.
Autologous means derived from the same individual.
Lipoaspiration Collection Kit (LCK)
The Lipoaspiration Collection Kit (LCK) contains all of the sterile disposables needed for a single, minimally invasive liposuction procedure, including sterile drape, tissue collection cannula, and items for tumescent infusion.
Liposuction is a cosmetic surgical procedure in which excess adipose tissue is extracted from a specific area of the body by suction.
InGeneron’s proprietary Matrase™ enzyme blend is a high purity enzymatic mixture for the release of stem cells and other regenerative cells from adipose tissue.
Non Advanced Therapy Medicinal Products (Non-ATMP)
Companies can consult the European Medicines Agency (EMA) to receive the classification as Advanced Therapy Medicinal Products (ATMP) or non Advanced Therapy Medicinal Products (non-ATMP) for new medical products for gene therapy, cell therapy, and tissue engineering.
A wound that does not improve after four weeks or does not heal within eight weeks is defined as a non-healing wound.
Platelet-Rich Plasma (PRP)
Platelet-rich plasma (PRP) is blood plasma that has been enriched with platelets and that serves as a concentrated source of autologous platelets.
Rotator cuff is the medical term for a group of tendons and muscles in the shoulder that connect the upper arm to the shoulder blade.
Stem cells are biological cells that are undifferentiated yet and can therefore differentiate into specialized cells as well as divide to produce more stem cells.
Stromal Vascular Fraction (SVF)
Stromal vascular fraction (SVF) is a component of the lipoaspirate.
Tendinopathy is the medical term for a tendon injury and includes both inflammation as well as microtears of the tendon.
Tumescent solution is a dilute solution of lidocaine, epinephrine, and sodium bicarbonate that is usually injected in the subcutaneous tissue during liposuction or burn surgery.